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These additional peptides included a conjugate with selective chemical substitution in the peptide to suppress glucagon activity, a compound with a linker that proved metabolically stable and was incapable of intracellular T3 release, and a third control conjugate that carried a metabolically-inert thyroid hormone

Nat Med 2001

It has been studied for its potential role in nerve regeneration and brain recovery following injuries like traumatic brain injury (TBI) or stroke

Curhan GC, Speizer FE, Hunter DJ et al: Epidemiology of interstitial cystitis: A population based study

We will now proceed to briefly review the current clinical management and therapeutic perspectives for SCA3, and more importantly, we will provide a critical view on how specific characteristics of this disease should guide the evolution of translational research and clinical trials (Fig